Franz Kehl Selected Research

triphenyltetrazolium

9/2014	The Role of Cyclooxygenase-1 and -2 in Sevoflurane-Induced Postconditioning Against Myocardial Infarction.
6/2013	Endothelial nitric oxide synthase mediates the first and inducible nitric oxide synthase mediates the second window of desflurane-induced preconditioning.
4/2011	Propofol inhibits desflurane-induced preconditioning in rabbits.
12/2009	Differential role of Pim-1 kinase in anesthetic-induced and ischemic preconditioning against myocardial infarction.
10/2009	Desflurane-induced preconditioning has a threshold that is lowered by repetitive application and is mediated by beta 2-adrenergic receptors.
3/2009	Desflurane-induced postconditioning is mediated by beta-adrenergic signaling: role of beta 1- and beta 2-adrenergic receptors, protein kinase A, and calcium/calmodulin-dependent protein kinase II.
7/2008	Differential role of calcium/calmodulin-dependent protein kinase II in desflurane-induced preconditioning and cardioprotection by metoprolol: metoprolol blocks desflurane-induced preconditioning.
2/2008	Activation of mitochondrial large-conductance calcium-activated K+ channels via protein kinase A mediates desflurane-induced preconditioning.
11/2006	Systematic evaluation of a novel model for cardiac ischemic preconditioning in mice.
10/2006	Desflurane-induced preconditioning against myocardial infarction is mediated by nitric oxide.

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Franz Kehl Research Topics

Disease

24	Infarction (Infarctions) 09/2014 - 01/2002
24	Myocardial Infarction 09/2014 - 01/2002
8	Ischemia 01/2012 - 11/2002
4	Hyperglycemia 04/2008 - 01/2002
2	Reperfusion Injury 01/2012 - 10/2009
2	Myocardial Ischemia (Ischemic Heart Diseases) 02/2011 - 11/2002
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 02/2004 - 04/2002
1	Hiccup (Hiccups) 06/2011
1	Coronary Occlusion 10/2009
1	Wounds and Injuries (Trauma) 07/2009
1	Heart Arrest (Cardiac Arrest) 02/2005
1	Brain Ischemia (Cerebral Ischemia) 02/2005
1	Hypoxia (Hypoxemia) 09/2004
1	Cardiomyopathies (Cardiomyopathy) 12/2003
1	Left Ventricular Dysfunction 12/2003
1	Hyperemia 12/2002
1	Diabetes Mellitus 06/2002
1	Ventricular Tachycardia 05/2002

Drug/Important Bio-Agent (IBA)

19	triphenyltetrazoliumIBA 09/2014 - 01/2002
14	Desflurane (I 653)FDA Link 01/2012 - 09/2006
9	Anesthetics (Anesthetic Agents)IBA 01/2012 - 01/2002
9	Isoflurane FDA LinkGeneric 10/2009 - 01/2002
5	Sevoflurane (Ultane)FDA LinkGeneric 09/2014 - 09/2004
4	Evans Blue (Blue, Evans)FDA Link 06/2013 - 11/2006
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2008 - 12/2002
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 03/2011 - 01/2011
2	DNA (Deoxyribonucleic Acid)IBA 03/2011 - 01/2011
2	ICI 118551IBA 10/2009 - 03/2009
2	N- (2- (4- bromocinnamylamino)ethyl)- 5- isoquinolinesulfonamide (h89)IBA 03/2009 - 09/2006
2	KN 93IBA 03/2009 - 07/2008
2	esmolol (Brevibloc)FDA LinkGeneric 03/2009 - 09/2006
2	20-hydroxy-5,8,11,14-eicosatetraenoic acidIBA 02/2004 - 04/2002
2	Blood Glucose (Blood Sugar)IBA 06/2003 - 06/2002
2	Ethanol (Ethyl Alcohol)IBA 04/2003 - 04/2002
2	Adenosine Triphosphate (ATP)IBA 06/2002 - 01/2002
1	SC 560IBA 09/2014
1	Cyclooxygenase 1IBA 09/2014
1	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA 09/2014
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 09/2014
1	Anastrozole (Arimidex)FDA LinkGeneric 01/2012
1	Aromatase (CYP19)IBA 01/2012
1	Estrogens (Estrogen)FDA Link 01/2012
1	phospholipid emulsion soybean oil (Intralipid)IBA 04/2011
1	EmulsionsIBA 04/2011
1	Propofol (Diprivan)FDA LinkGeneric 04/2011
1	NitratesIBA 03/2011
1	NitritesIBA 03/2011
1	Adenosine Monophosphate (AMP)IBA 02/2011
1	Protein Kinases (Protein Kinase)IBA 02/2011
1	GlycogenIBA 02/2011
1	Proto-Oncogene Proteins c-pim-1 (Proto Oncogene Proteins c pim 1)IBA 12/2009
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 12/2009
1	Metoprolol (Toprol-XL)FDA LinkGeneric 07/2008
1	Simvastatin (Zocor)FDA LinkGeneric 04/2008
1	arginine methyl esterIBA 04/2008
1	Troponin IIBA 11/2006
1	Nitric Oxide Synthase (NO Synthase)IBA 10/2006
1	Arginine (L-Arginine)FDA Link 10/2006
1	Inhalation AnestheticsIBA 09/2004
1	Vasoconstrictor AgentsIBA 02/2004
1	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2003
1	Glucose (Dextrose)FDA LinkGeneric 06/2003
1	Saline SolutionIBA 06/2003
1	Acetylcysteine (Siran)FDA LinkGeneric 06/2003
1	Adenosine (Adenocard)FDA LinkGeneric 04/2003
1	ProstaglandinsIBA 12/2002
1	Superoxides (Superoxide)IBA 12/2002
1	AcidsIBA 12/2002
1	propenylphosphonic acidIBA 12/2002
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 12/2002
1	Oxygen (Dioxygen)IBA 05/2002
1	Free RadicalsIBA 05/2002
1	Potassium Channels (Potassium Channel)IBA 01/2002

Therapy/Procedure

6	Microspheres (Microsphere) 06/2003 - 01/2002
1	Vagus Nerve Stimulation 06/2011
1	Laryngoscopes 07/2009
1	Resuscitation 02/2005